Alternative pathways of acrosome reaction induction
نویسندگان
چکیده
منابع مشابه
The Acrosome Reaction In
Suspensions of Mytilus edulis eggs were fixed with osmium tetroxide at various intervals between 1 and l0 seconds after heavy insemination, and sectioned for electron microscopy to follow the natural process of acrosome reaction in the spermatozoa around the eggs. Sperm suspensions were also fixed after the addition of I0 per cent by volume of M/3 calcium chloride. Within the first second after...
متن کاملRegulating the acrosome reaction.
The acrosome reaction is a secretory event that must be completed by the sperm of many animal species prior to fusion with eggs. In mammals, exocytosis in triggered by ZP3, a glycoprotein component of the egg pellucida, following gamete contact. ZP3 promotes a sustained influx of Ca2+ into sperm that is necessary for the acrosome reaction. Here, we discuss the mechanism by which ZP3 generates C...
متن کاملModulation of spermatozoon acrosome reaction.
Spermatozoon acrosome reaction is an exocytotic event of the utmost importance for the development of mammalian fertilisation. Current evidence shows that the triggering of the acrosome reaction (AR) could be regulated by the action of diverse compounds, namely, metabolites, neurotransmitters and hormones. The aim of the present review is to describe the modulating effects of several compounds ...
متن کاملIntracellular events and signaling pathways involved in sperm acquisition of fertilizing capacity and acrosome reaction.
Two processes, namely capacitation and acrosome reaction, are of fundamental importance in the fertilization of oocyte by spermatozoon. Physiologically occurring in the female genital tract, capacitation is a complex process, which renders the sperm cell capable for specific interaction with the oocyte. During capacitation, modification of membrane characteristics, enzyme activity and motility ...
متن کاملAcrosome reaction: relevance of zona pellucida glycoproteins.
During mammalian fertilisation, the zona pellucida (ZP) matrix surrounding the oocyte is responsible for the binding of the spermatozoa to the oocyte and induction of the acrosome reaction (AR) in the ZP-bound spermatozoon. The AR is crucial for the penetration of the ZP matrix by spermatozoa. The ZP matrix in mice is composed of three glycoproteins designated ZP1, ZP2 and ZP3, whereas in human...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 1996
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/2.10.813